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By measuring the combined strength of cell-cell / cell-protein binding with controlled forces, Cell Avidity generates direct, physiologically relevant measurements of binding in its full, dynamic complexity. Applied to cell or antibody binding research, in experiments on functional modifications or microenvironment modulators, Cell Avidity is shown to reveal the mechanisms of action, facilitating rational design choices, selecting the right candidates fast and early, and ultimately improving therapeutic outcomes.

To support progress in immunotherapy, we need to measure binding the way it happens—in real life, in real cells.

This is Cell Avidity.

What if you could measure molecular properties and interactions while simultaneously recording and showing you the processes in real-time? A technology that can reveal the crucial and dynamic interactions taking place at the molecular level and gives you direct proof of the mechanisms involved. A tool that can provide an understanding of the root of disease development at the molecular level and accelerate therapeutic breakthroughs.

Dynamic Single-Molecule combines live visualization, manipulation, and force measurement at the smallest molecular scale, leads to single-molecule imaging and base-pair resolution measurements of the interactions between biomolecules. Taken together, this provides – for the first time – the crucial dynamic and functional mechanistic information that is complementary to molecular structure, bulk functional assays, and cell imaging.